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药物肽

Drug peptide

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Lanreotide Acetate

发布时间:2022-06-08作者:南京杰肽生物科技有限公司

CAS No.:
127984-74-1/108736-35-2

Molecular formula:
C54H69N11O10S2

Molecular Weight:

Amino acids sequence:
H-D-2-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Disulfide bond)

Application:
Lanreotide Acetate is the acetate salt of a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.

Notes: For research use only

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